Neurodegeneration And Brain Health
Key Indications: Spermidine can trigger the activation of autophagy which may remove harmful toxic proteins causing diseases such as Parkinson's, Alzheimers, or ALS. This effect was discovered in mice as well as human studies.
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43.
Influence of microRNA deregulation on chaperone-mediated autophagy and a-synuclein pathology in Parkinson's disease. Learn More >
Induction of autophagy by spermidine is neuroprotective via inhibition of caspase 3-mediated Beclin 1 cleavage. Learn More >